Ackr1^tm1Skmz
Targeted Allele Detail

Summary

• Symbol: Ackr1^tm1Skmz
• Name: atypical chemokine receptor 1 (Duffy blood group); targeted mutation 1, Kazuhisa Sekimizu
• MGI ID: MGI:2656980
• Gene: Ackr1 Location: Chr1:173159457-173161079 bp, - strand Genetic Position: Chr1, 80.33 cM
• Alliance: Ackr1^tm1Skmz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82938
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The gene was disrupted by replacement of exon 1 and part of exon 2 with a neomycin resistant cassette via homologous recombination. (J:82938)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ackr1 Mutation: 24 strains or lines available

References

• Original: J:82938 Fukuma N, et al., A role of the Duffy antigen for the maintenance of plasma chemokine concentrations. Biochem Biophys Res Commun. 2003 Mar 28;303(1):137-9
• All: 1 reference(s)