Fgfr1^tm1.1Jpa
Targeted Allele Detail

Summary

• Symbol: Fgfr1^tm1.1Jpa
• Name: fibroblast growth factor receptor 1; targeted mutation 1.1, Juha Partanen
• MGI ID: MGI:2657013
• Synonyms: Fgfr1^deltaflox
• Gene: Fgfr1 Location: Chr8:26008808-26067819 bp, + strand Genetic Position: Chr8, 14.12 cM
• Alliance: Fgfr1^tm1.1Jpa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:83004
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed region encompassing exons 8 through 15 was excised via cre-mediated recombination in the germline. (J:83004)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgfr1 Mutation: 223 strains or lines available

References

• Original: J:83004 Trokovic R, et al., FGFR1 is independently required in both developing mid- and hindbrain for sustained response to isthmic signals. EMBO J. 2003 Apr 15;22(8):1811-23
• All: 9 reference(s)