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Pax2tm1Cjt
Targeted Allele Detail
Summary
Symbol: Pax2tm1Cjt
Name: paired box 2; targeted mutation 1, Clifford J Tabin
MGI ID: MGI:2657223
Gene: Pax2  Location: Chr19:44744484-44826310 bp, + strand  Genetic Position: Chr19, 38.09 cM
Alliance: Pax2tm1Cjt page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:74492
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA lacZ gene and neomycin selection cassette was inserted in frame into exon 1. However, this allele does not express functional beta-galactosidase. (J:74492)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 3 assay results
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pax2 Mutation:  44 strains or lines available
References
Original:  J:74492 Heanue TA, et al., Dach1, a vertebrate homologue of Drosophila dachshund, is expressed in the developing eye and ear of both chick and mouse and is regulated independently of Pax and Eya genes. Mech Dev. 2002 Feb;111(1-2):75-87
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory