Pax2^tm1Cjt
Targeted Allele Detail

Summary

• Symbol: Pax2^tm1Cjt
• Name: paired box 2; targeted mutation 1, Clifford J Tabin
• MGI ID: MGI:2657223
• Gene: Pax2 Location: Chr19:44744484-44826310 bp, + strand Genetic Position: Chr19, 38.09 cM
• Alliance: Pax2^tm1Cjt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:74492
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A lacZ gene and neomycin selection cassette was inserted in frame into exon 1. However, this allele does not express functional beta-galactosidase. (J:74492)

Expression

In Mice Carrying this Mutation:	3 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pax2 Mutation: 44 strains or lines available

References

• Original: J:74492 Heanue TA, et al., Dach1, a vertebrate homologue of Drosophila dachshund, is expressed in the developing eye and ear of both chick and mouse and is regulated independently of Pax and Eya genes. Mech Dev. 2002 Feb;111(1-2):75-87
• All: 1 reference(s)