Atrn^mg-6J
Spontaneous Allele Detail

Summary

• Symbol: Atrn^mg-6J
• Name: attractin; mahogany 6 Jackson
• MGI ID: MGI:2657306
• Gene: Atrn Location: Chr2:130748415-130872253 bp, + strand Genetic Position: Chr2, 63.26 cM
• Alliance: Atrn^mg-6J page

Mutation origin

• Strain of Origin: CAST/EiJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: This mutation has a genomic deletion which encompasses much of the Atrn gene including the N-terminus, but not the C-terminus. The last two coding exons are not deleted. Northern blot analysis of total brain RNA failed to detect Atrn transcript in mice homozygous for this allele. (J:96070)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Atrn Mutation: 90 strains or lines available

References

• Original: J:96070 Bronson RT, et al., Mice with mutations in the mahogany gene Atrn have cerebral spongiform changes. J Neuropathol Exp Neurol. 2001 Jul;60(7):724-30
• All: 2 reference(s)