Dync1h1^Cra1
Chemically induced Allele Detail

Summary

• Symbol: Dync1h1^Cra1
• Name: dynein cytoplasmic 1 heavy chain 1; cramping 1
• MGI ID: MGI:2661085
• Synonyms: Cra, Cra1
• Gene: Dync1h1 Location: Chr12:110567886-110633379 bp, + strand Genetic Position: Chr12, 60.7 cM
• Alliance: Dync1h1^Cra1 page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: Cra1 was found to be allelic to Loa through complementation testing. The mutation in the Cra mouse was identified as A to G mutation that results in the amino acid convertion tyrosine 1055 to a cysteine (Y1055C). (J:83128)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dync1h1 Mutation: 195 strains or lines available

References

• Original: J:68708 Hrabe de Angelis MH, et al., Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet. 2000 Aug;25(4):444-7
• All: 10 reference(s)