Dync1h1^tm1Noh
Targeted Allele Detail

Summary

• Symbol: Dync1h1^tm1Noh
• Name: dynein cytoplasmic 1 heavy chain 1; targeted mutation 1, Nobutaka Hirokawa
• MGI ID: MGI:2661091
• Synonyms: cDHC-
• Gene: Dync1h1 Location: Chr12:110567886-110633379 bp, + strand Genetic Position: Chr12, 60.7 cM
• Alliance: Dync1h1^tm1Noh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:78610
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A replacement construct containing a PGK-neo cassette was inserted in the reverse orientation and replaced the second half of the first exon and the first intron of the gene. (J:78610)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dync1h1 Mutation: 195 strains or lines available

References

• Original: J:78610 Harada A, et al., Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein. J Cell Biol. 1998 Apr 6;141(1):51-9
• All: 1 reference(s)