Lmr5^BALB/cHeA
QTL Variant Detail

Summary

• QTL variant: Lmr5^BALB/cHeA
• Name: leishmaniasis resistance 5; BALB/cHeA
• MGI ID: MGI:2661168
• QTL: Lmr5 Location: Chr10:116220635-122179828 bp Genetic Position: Chr10, cM position of peak correlated region/allele: 73.57 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: BALB/cHeA

Variant description

• Allele Type: QTL
• Mutation: Undefined
• Mutation details: This allele is associated with increased skin lesion size and high serum IgE, IL-12, and IFN-gamma compared to STS/A. (J:82715)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

References

• Original: J:82715 Lipoldova M, et al., Susceptibility to Leishmania major infection in mice: multiple loci and heterogeneity of immunopathological phenotypes. Genes Immun. 2000 Feb;1(3):200-6
• All: 1 reference(s)