Lmr8^CcS20/Dem
QTL Variant Detail

Summary

• QTL variant: Lmr8^CcS20/Dem
• Name: leishmaniasis resistance 8; CcS20/Dem
• MGI ID: MGI:2661178
• QTL: Lmr8 Location: Chr1:156602037-189303617 bp Genetic Position: Chr1, cM position of peak correlated region/allele: 67.71 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: CcS20/Dem

Variant description

• Allele Type: QTL
• Inheritance: Other (see notes)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Notes

Homozygosity for BALB/cHeA alleles at Lrm11 and homozygosity for STS/A alleles at Lmr8 confers decreased IgE levels.

Lmr8 exhibits additive inheritance.

References

• Original: J:82717 Badalova J, et al., Separation and mapping of multiple genes that control IgE level in Leishmania major infected mice. Genes Immun. 2002 Jun;3(4):187-95
• All: 1 reference(s)