Kcnq2^Nmf134
Chemically induced Allele Detail

Summary

• Symbol: Kcnq2^Nmf134
• Name: potassium voltage-gated channel, subfamily Q, member 2; neuroscience mutagenesis facility, 134
• MGI ID: MGI:2661797
• Synonyms: Kcnq2^V182M
• Gene: Kcnq2 Location: Chr2:180717372-180777093 bp, - strand Genetic Position: Chr2, 103.57 cM, cytoband H3-4
• Alliance: Kcnq2^Nmf134 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A G-to-A transversion mutation in codon 182 results in the substitution of methionine for valine at this highly conserved position in the encoded protein. (J:136510)
• Inheritance: Semidominant

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kcnq2 Mutation: 50 strains or lines available

References

• Original: J:82238 JAX Neuroscience Mutagenesis Facility, Heritable mouse mutants from JAX NMF ENU Mutagenesis Program. MGI Direct Data Submission. 2003
• All: 3 reference(s)