Pou5f2^tm1Rsd
Targeted Allele Detail

Summary

• Symbol: Pou5f2^tm1Rsd
• Name: POU domain class 5, transcription factor 2; targeted mutation 1, Michael G Rosenfeld
• MGI ID: MGI:2661927
• Gene: Pou5f2 Location: Chr13:78173021-78174414 bp, + strand Genetic Position: Chr13, 41.38 cM, cytoband C1
• Alliance: Pou5f2^tm1Rsd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:41753
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The entire coding region was replaced with a neomycin cassette inserted by homologous recombination. (J:41753)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pou5f2 Mutation: 14 strains or lines available

References

• Original: J:41753 Pearse RV 2nd, et al., Reduced fertility in mice deficient for the POU protein sperm-1. Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7555-60
• All: 1 reference(s)