Tg(ACTB-Mgat3)2Nta
Transgene Detail

Summary

• Symbol: Tg(ACTB-Mgat3)2Nta
• Name: transgene insertion 2, Naoyuki Taniguchi
• MGI ID: MGI:2662357
• Transgene: Tg(ACTB-Mgat3)2Nta Location: unknown
• Alliance: Tg(ACTB-Mgat3)2Nta page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(ACTB-Mgat3)2Nta expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Mgat3 (29582)

  Mgat3

  (MGI:104532)

• Mutation details: The transgene consists of a human ACTB promoter and a rat Mgat3 cDNA sequence. Enzyme assays demonstrate increased Mgat3 activity in the bone marrow, spleen, and peripheral blood of transgenic animals. (J:80227)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:80227 Yoshimura M, et al., Bisecting GlcNAc structure is implicated in suppression of stroma-dependent haemopoiesis in transgenic mice expressing N-acetylglucosaminyltransferase III. Biochem J. 1998 May 1;331(Pt 3):733-42
• All: 2 reference(s)