Myb^tm1Ssp
Targeted Allele Detail

Summary

• Symbol: Myb^tm1Ssp
• Name: myeloblastosis oncogene; targeted mutation 1, S Steven Potter
• MGI ID: MGI:2662859
• Gene: Myb Location: Chr10:21000834-21036883 bp, - strand Genetic Position: Chr10, 9.75 cM
• Alliance: Myb^tm1Ssp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:43747
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• The endogenous locus was disrupted by the insertion of a neomycin selection cassette into exon 6. (J:43747)

Expression

In Mice Carrying this Mutation:	56 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Myb Mutation: 53 strains or lines available

References

• Original: J:43747 Mucenski ML, et al., A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell. 1991 May 17;65(4):677-89
• All: 28 reference(s)