Bag4^tm1Yeh
Targeted Allele Detail

Summary

• Symbol: Bag4^tm1Yeh
• Name: BCL2-associated athanogene 4; targeted mutation 1, Wen-Chen Yeh
• MGI ID: MGI:2663613
• Synonyms: SODD^-
• Gene: Bag4 Location: Chr8:26254566-26275237 bp, - strand Genetic Position: Chr8, 14.17 cM, cytoband A3
• Alliance: Bag4^tm1Yeh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:83559
• Parent Cell Line: E14K (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The gene was disrupted by replacement of exon 2 with a PGK-neo cassette via homologous recombination. Absence of gene expression was confirmed by Western blot analysis of primary embryonic fibroblasts derived from homozygous mutants. (J:83559)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bag4 Mutation: 33 strains or lines available

References

• Original: J:83559 Takada H, et al., Role of SODD in regulation of tumor necrosis factor responses. Mol Cell Biol. 2003 Jun;23(11):4026-33
• All: 2 reference(s)