Maff^tm1.1Jeng
Targeted Allele Detail

Summary

• Symbol: Maff^tm1.1Jeng
• Name: v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian); targeted mutation 1.1, James Douglas Engel
• MGI ID: MGI:2663639
• Gene: Maff Location: Chr15:79230821-79243276 bp, + strand Genetic Position: Chr15, 37.7 cM
• Alliance: Maff^tm1.1Jeng page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:56405
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: As in Maff^tm1Jeng, the entire coding region, except for the first 3 codons, was replaced with a cassette containing lacZ and a floxed selection region. Prior to implantation and germline transmission, the floxed region was excised via cre mediated recombination, leaving lacZ intact. (J:56405)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Maff Mutation: 8 strains or lines available

References

• Original: J:56405 Onodera K, et al., Characterization of the murine mafF gene. J Biol Chem. 1999 Jul 23;274(30):21162-9
• All: 5 reference(s)