Hint1^tm1.1Tpm
Targeted Allele Detail

Summary

• Symbol: Hint1^tm1.1Tpm
• Name: histidine triad nucleotide binding protein 1; targeted mutation 1.1, Tomi P Makela
• MGI ID: MGI:2663678
• Synonyms: Hint^-
• Gene: Hint1 Location: Chr11:54757209-54761327 bp, + strand Genetic Position: Chr11, 32.13 cM
• Alliance: Hint1^tm1.1Tpm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:83562
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele is derived from Hint^tm1Tpm by crossing mutant animals to cre deleter strain Tg(Pgk1-cre)1Lni. Exons 2 and 3 were deleted by homologous recombination between flanking loxP sites. A single loxP site and a PGK-neo cassette remains in the place of exon 2 and exon 3. (J:83562)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hint1 Mutation: 25 strains or lines available

References

• Original: J:83562 Korsisaari N, et al., The histidine triad protein Hint is not required for murine development or Cdk7 function. Mol Cell Biol. 2003 Jun;23(11):3929-35
• All: 1 reference(s)