Etv1^tm1Wds
Targeted Allele Detail

Summary

• Symbol: Etv1^tm1Wds
• Name: ets variant 1; targeted mutation 1, William D Snider
• MGI ID: MGI:2663693
• Synonyms: Er81^flox
• Gene: Etv1 Location: Chr12:38829655-38920484 bp, + strand Genetic Position: Chr12, 17.99 cM
• Alliance: Etv1^tm1Wds page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:83461
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 11, encoding the DNA binding ETS domain, was flanked by a single loxP site in intron 10 and a floxed neo cassette in intron 11. (J:83461)

Expression

In Mice Carrying this Mutation:

3 assay results 3 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Etv1^tm1Wds

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Etv1 Mutation: 44 strains or lines available

References

• Original: J:83461 Patel TD, et al., Peripheral NT3 signaling is required for ETS protein expression and central patterning of proprioceptive sensory afferents. Neuron. 2003 May 8;38(3):403-16
• All: 13 reference(s)