Tg(Gfap-cre)2Brn
Transgene Detail

Summary

• Symbol: Tg(Gfap-cre)2Brn
• Name: transgene insertion 2, Anton Berns
• MGI ID: MGI:2663939
• Synonyms: GFAP-Cre, GFAP/Cre, mGFAP-Cre
• Transgene: Tg(Gfap-cre)2Brn Location: unknown
• Alliance: Tg(Gfap-cre)2Brn page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Gfap-cre)2Brn expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gfap (MGI:95697)

• Mutation details: Transgene expressing bacteriophage P1 Cre recombinase under control of the mouse Gfap promoter. This transgene is expressed in the developing forebrain and in the spinal ganglia and also in scattered precursor cells located in the EGL of the cerebellum. (J:61961)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gfap (mouse) Summary of all recombinase alleles driven by Gfap. Comparative matrix view of recombinase activities Alliance mouse Gfap gene page

Disease models

Tumor Data

List all tumor models in MMHCdb carrying Tg(Gfap-cre)2Brn

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:61961 Marino S, et al., Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum. Genes Dev. 2000 Apr 15;14(8):994-1004
• All: 11 reference(s)