Tg(INS-cre)2Rms
Transgene Detail

Summary

• Symbol: Tg(INS-cre)2Rms
• Name: transgene insertion 2, Robyn M Slattery
• MGI ID: MGI:2663956
• Synonyms: HIP-Cre
• Transgene: Tg(INS-cre)2Rms Location: unknown
• Alliance: Tg(INS-cre)2Rms page

Transgene origin

• Strain of Origin: NOD

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(INS-cre)2Rms expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  INS (3630)

  Ins1	(MGI:96572)
  Ins2	(MGI:96573)

• Mutation details: The transgene consists of a human insulin promoter and cre. The human insulin promoter (INS) drives cre expression in beta islet cells. (J:83635)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	INS (human) Summary of all recombinase alleles driven by INS. Alliance human INS gene page

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:83635 Hamilton-Williams EE, et al., Beta cell MHC class I is a late requirement for diabetes. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6688-93
• All: 2 reference(s)