Tnfrsf9^tm1Byk
Targeted Allele Detail

Summary

• Symbol: Tnfrsf9^tm1Byk
• Name: tumor necrosis factor receptor superfamily, member 9; targeted mutation 1, Byoung Kwon
• MGI ID: MGI:2664914
• Synonyms: 4-1BB^-, 4-1BB-KO, CD137^-
• Gene: Tnfrsf9 Location: Chr4:151004612-151030561 bp, + strand Genetic Position: Chr4, 81.52 cM
• Alliance: Tnfrsf9^tm1Byk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:83996
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: The gene was disrupted by insertion of a neomycin resistance cassette into the translation initiation site. (J:83996)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Tnfrsf9 Mutation: 49 strains or lines available

References

• Original: J:83996 Kwon BS, et al., Immune responses in 4-1BB (CD137)-deficient mice. J Immunol. 2002 Jun 1;168(11):5483-90
• All: 54 reference(s)