Tg(Krt14-MYCER)2184C.1Fmw
Transgene Detail

Summary

• Symbol: Tg(Krt14-MYCER)2184C.1Fmw
• Name: transgene insertion 2184C.1, Fiona M Watt
• MGI ID: MGI:2667449
• Synonyms: K14MycER
• Transgene: Tg(Krt14-MYCER)2184C.1Fmw Location: unknown
• Alliance: Tg(Krt14-MYCER)2184C.1Fmw page

Transgene origin

• Strain of Origin: (CBA x C57BL/6)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Krt14-MYCER)2184C.1Fmw expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  MYC (4609)

  Bmyc	(MGI:88184)
  Myc	(MGI:97250)

• Mutation details: A keratin 14 promoter was used to drive expression of a tamoxifen inducible form of human MYC. Founder line 2184C.1 had 70 copies of the transgene. (J:68931)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:68931 Arnold I, et al., c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny. Curr Biol. 2001 Apr 17;11(8):558-68
• All: 11 reference(s)