Dclre1c^tm1.1Fwa
Targeted Allele Detail

Summary

• Symbol: Dclre1c^tm1.1Fwa
• Name: DNA cross-link repair 1C; targeted mutation 1.1, Frederick W Alt
• MGI ID: MGI:2667616
• Synonyms: Art^L
• Gene: Dclre1c Location: Chr2:3425168-3465167 bp, + strand Genetic Position: Chr2, 1.93 cM
• Alliance: Dclre1c^tm1.1Fwa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:80995
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A single loxP site was left in place of exons 5 and 6 after the floxed neo cassette was removed from Dclre1c^tm1Fwa ES cells via cre-mediated recombination. (J:80995)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dclre1c Mutation: 31 strains or lines available

References

• Original: J:80995 Rooney S, et al., Leaky scid phenotype associated with defective v(d)j coding end processing in artemis-deficient mice. Mol Cell. 2002 Dec;10(6):1379-90
• All: 9 reference(s)