Matk^tm1Suda
Targeted Allele Detail

Summary

• Symbol: Matk^tm1Suda
• Name: megakaryocyte-associated tyrosine kinase; targeted mutation 1, Toshio Suda
• MGI ID: MGI:2668016
• Synonyms: CHK/HYL-
• Gene: Matk Location: Chr10:81088769-81098819 bp, + strand Genetic Position: Chr10, 39.72 cM, cytoband C1
• Alliance: Matk^tm1Suda page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:34080
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• The endogenous allele was disrupted by the insertion of a neomycin selection cassette into exon 4. (J:34080)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Matk Mutation: 30 strains or lines available

References

• Original: J:34080 Hamaguchi I, et al., Analysis of CSK homologous kinase (CHK/HYL) in hematopoiesis by utilizing gene knockout mice. Biochem Biophys Res Commun. 1996 Jul 5;224(1):172-9
• All: 1 reference(s)