Txn1^tm1Mmt
Targeted Allele Detail

Summary

• Symbol: Txn1^tm1Mmt
• Name: thioredoxin 1; targeted mutation 1, Maketo M Taketo
• MGI ID: MGI:2669963
• Synonyms: Trx-KO, Txn -
• Gene: Txn1 Location: Chr4:57943373-57956411 bp, - strand Genetic Position: Chr4, 31.87 cM
• Alliance: Txn1^tm1Mmt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:35059
• Parent Cell Line: D3a2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin selection cassette replaced a genomic fragment containing translation start codon. (J:35059)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Txn1 Mutation: 15 strains or lines available

References

• Original: J:35059 Matsui M, et al., Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene. Dev Biol. 1996 Aug 25;178(1):179-85
• All: 3 reference(s)