Wasf2^tm1Tta
Targeted Allele Detail

Summary

• Symbol: Wasf2^tm1Tta
• Name: WASP family, member 2; targeted mutation 1, Tadaomi Takenawa
• MGI ID: MGI:2670134
• Synonyms: WAVE2^-
• Gene: Wasf2 Location: Chr4:132857843-132927067 bp, + strand Genetic Position: Chr4, 66.22 cM
• Alliance: Wasf2^tm1Tta page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:84651
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The exon encoding the start codon was replaced with a neo cassette. Protein was undetected by Western blot analysis of homozygous mutant mice. (J:84651)

Expression

In Mice Carrying this Mutation:	20 assay results
In Structures Affected by this Mutation:	14 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wasf2 Mutation: 120 strains or lines available

References

• Original: J:84651 Yamazaki D, et al., WAVE2 is required for directed cell migration and cardiovascular development. Nature. 2003 Jul 24;424(6947):452-6
• All: 1 reference(s)