kkt
Transgenic Allele Detail

Summary

• Symbol: kkt
• Name: kyphoscoliosis kinked tail
• MGI ID: MGI:2670329
• Gene: kkt Location: unknown Genetic Position: Chr2, cytoband G-H
• Alliance: kkt page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic
• Mutations: Deletion, Insertion
• kkt involves 1 genes/genome features (kkt) View all
• Mutation details: The kkt mutant mouse was produced by the random insertion of a fusion transgene in which the myogenin promoter was used to direct expression of a human myf5 cDNA-IRESLacZ bicistronic transcript. Heterozygous animals contain about 15 copies of the transgene as determined by Southern blot analysis. Southern blot analysis suggested that a small deletion of less than 10 kb exists at the transgene integration site. (J:60410)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

13 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any kkt Mutation: 0 strains or lines available

References

• Original: J:60410 Bialek P, et al., Characterization of a novel insertional mouse mutation, kkt: A closely linked modifier of Pax1. Dev Biol. 2000 Feb 15;218(2):354-66
• All: 1 reference(s)