Sema3f^tm1.1Ddg
Targeted Allele Detail

Summary

• Symbol: Sema3f^tm1.1Ddg
• Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F; targeted mutation 1.1, David D Ginty
• MGI ID: MGI:2670662
• Synonyms: sema3F C
• Gene: Sema3f Location: Chr9:107558699-107587674 bp, - strand Genetic Position: Chr9, 58.91 cM, cytoband F2
• Alliance: Sema3f^tm1.1Ddg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:84687
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The FRT flanked neo cassette located 4 kb upstream of exon 1 was removed from Sema3f^tm1Ddg by in vivo FRT-mediated recombination. A region extending from 4 kb upstream of exon 1 through 1 kb of intron 1 remained flanked by single loxP sites. (J:84687)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sema3f Mutation: 41 strains or lines available

References

• Original: J:84687 Sahay A, et al., Semaphorin 3F is critical for development of limbic system circuitry and is required in neurons for selective CNS axon guidance events. J Neurosci. 2003 Jul 30;23(17):6671-80
• All: 4 reference(s)