Lmo2^tm2(cre)Thr
Targeted Allele Detail

Summary

• Symbol: Lmo2^tm2(cre)Thr
• Name: LIM domain only 2; targeted mutation 2, Terence H Rabbitts
• MGI ID: MGI:2671438
• Synonyms: Lmo2-cre
• Gene: Lmo2 Location: Chr2:103788331-103812223 bp, + strand Genetic Position: Chr2, 54.46 cM
• Alliance: Lmo2^tm2(cre)Thr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:84518
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Lmo2^tm2(cre)Thr expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lmo2 (MGI:102811)

• Mutation details: Sequence encoding cre recombinase was inserted into the endogenous locus via homologous recombination. (J:84518)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lmo2 (mouse) Summary of all recombinase alleles driven by Lmo2. Alliance mouse Lmo2 gene page

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lmo2 Mutation: 31 strains or lines available

References

• Original: J:84518 Forster A, et al., Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer. Cancer Cell. 2003 May;3(5):449-58
• All: 4 reference(s)