Alg10b^nse5
Chemically induced Allele Detail

Summary

• Symbol: Alg10b^nse5
• Name: ALG10 alpha-1,2-glucosyltransferase; neurological/sensory 5
• MGI ID: MGI:2671810
• Synonyms: Deaf1, nse^m05Jus
• Gene: Alg10b Location: Chr15:90108514-90117674 bp, + strand Genetic Position: Chr15, 45.07 cM
• Alliance: Alg10b^nse5 page

Outer hair cells of the cochlea are abnormal in Alg10b^nse5/Alg10b^nse5 mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Mutagenesis for Dev. Defects

Mutation description

Allele Type: Chemically induced (ENU) Mutation: Single point mutation Mutation details: ENU-mutagenesis induced a point mutation that results in the amino acid substitution of serine for leucine at position 389 (L389S). (J:209766) Inheritance: Recessive

Identification of the mutation in the Alg10b^nse5 allele

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Alg10b Mutation: 20 strains or lines available

References

• Original: J:85113 Kile BT, et al., Functional genetic analysis of mouse chromosome 11. Nature. 2003 Sep 4;425(6953):81-6
• All: 2 reference(s)