About   Help   FAQ
Erbb2l11Jus8
Chemically induced Allele Detail
Summary
Symbol: Erbb2l11Jus8
Name: erb-b2 receptor tyrosine kinase 2; lethal, Chr 11, Justice 8
MGI ID: MGI:2671879
Synonyms: l11Jus08
Gene: Erbb2  Location: Chr11:98303310-98328542 bp, + strand  Genetic Position: Chr11, 61.75 cM, cytoband D
Alliance: Erbb2l11Jus8 page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Mutagenesis for Dev. Defects
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU mutagenesis induced a T to G point mutation that results in the amino acid susbtitution of arginine for methionine at position 802 (M802R). (J:222460)
Inheritance:    Recessive
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Erbb2 Mutation:  61 strains or lines available
Notes
Additional non-causative mutations identified in l11Jus08 mice include: T to C in Med31, T to A in Nf1. J:222460
References
Original:  J:85113 Kile BT, et al., Functional genetic analysis of mouse chromosome 11. Nature. 2003 Sep 4;425(6953):81-6
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory