Nxn^l11Jus13
Chemically induced Allele Detail

Summary

• Symbol: Nxn^l11Jus13
• Name: nucleoredoxin; lethal, Chr 11, Justice 13
• MGI ID: MGI:2671884
• Synonyms: Nxn^J13
• Gene: Nxn Location: Chr11:76148052-76289967 bp, - strand Genetic Position: Chr11, 45.92 cM
• Alliance: Nxn^l11Jus13 page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Mutagenesis for Dev. Defects

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This phenotypic mutant was identified in an ENU mutagenesis screen at the Baylor College of Medicine. A T-to-A point mutation occurs two base pairs after exon 6, resulting in alteration of a consensus splice donor sequence. RT-PCR and sequencing showed that the mutation results in aberrant splicing of the transcript. A noncomplementation test with a knockout allele confirmed that the mutation in this gene is responsible for the mutant phenotype. (J:161341)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nxn Mutation: 502 strains or lines available

References

• Original: J:85113 Kile BT, et al., Functional genetic analysis of mouse chromosome 11. Nature. 2003 Sep 4;425(6953):81-6
• All: 3 reference(s)