Med31^l11Jus15
Chemically induced Allele Detail

Summary

• Symbol: Med31^l11Jus15
• Name: mediator complex subunit 31; lethal, Chr 11, Justice 15
• MGI ID: MGI:2671886
• Gene: Med31 Location: Chr11:72102550-72106418 bp, - strand Genetic Position: Chr11, 43.93 cM, cytoband B4
• Alliance: Med31^l11Jus15 page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Mutagenesis for Dev. Defects

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a C to T mutation in exon 4 that is predicted to result in a truncation at amino acid 105 eliminating the last 26 amino acids. The absence of protein expression was confirmed by western blot analysis on embryo extracts. (J:161417)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Med31 Mutation: 15 strains or lines available

References

• Original: J:85113 Kile BT, et al., Functional genetic analysis of mouse chromosome 11. Nature. 2003 Sep 4;425(6953):81-6
• All: 3 reference(s)