Tg(Col2a1-cre)1Star
Transgene Detail

Summary

• Symbol: Tg(Col2a1-cre)1Star
• Name: transgene insertion 1, Rene St-Arnaud
• MGI ID: MGI:2671895
• Synonyms: alpha1(II)-Cre, alphaI(II)-collagen-cre, Col2-Cre
• Transgene: Tg(Col2a1-cre)1Star Location: unknown
• Alliance: Tg(Col2a1-cre)1Star page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Col2a1-cre)1Star expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Col2a1 (MGI:88452)

• Mutation details: Bacterial Cre recombinase cDNA was subcloned between a 3 kb fragment of the mouse Col2a1 promoter and its chondrocyte-specific enhancer region. Transgenic founders were generated by pronuclear injection. Confirmation that Cre was expressed as expected was accomplished by crossing transgenic mice with mice carrying the Rosa26 reporter gene (J:84273)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Col2a1 (mouse) Summary of all recombinase alleles driven by Col2a1. Comparative matrix view of recombinase activities Alliance mouse Col2a1 gene page

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:84273 Terpstra L, et al., Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes. J Cell Biol. 2003 Jul 7;162(1):139-48
• All: 26 reference(s)