Smo^tm1.1Pab
Targeted Allele Detail

Summary

• Symbol: Smo^tm1.1Pab
• Name: smoothened, frizzled class receptor; targeted mutation 1.1, Philip A Beachy
• MGI ID: MGI:2672132
• Synonyms: Smo^-, Smoⁿ
• Gene: Smo Location: Chr6:29735502-29761364 bp, + strand Genetic Position: Chr6, 12.36 cM, cytoband A3.3
• Alliance: Smo^tm1.1Pab page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:79457
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A portion of the first coding exon, including sequence encoding the start codon and the signal peptide, was deleted by cre mediated recombination. (J:79457)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smo Mutation: 39 strains or lines available

References

• Original: J:79457 Ma Y, et al., Hedgehog-Mediated Patterning of the Mammalian Embryo Requires Transporter-like Function of Dispatched. Cell. 2002 Oct 4;111(1):63
• All: 3 reference(s)