In(11Trp53;11Wnt3)8Brd
Targeted Allele Detail

Summary

• Symbol: In(11Trp53;11Wnt3)8Brd
• Name: inversion, Chr 11, Allan Bradley 8
• MGI ID: MGI:2673211
• Synonyms: In(11)8Brd, Inv(11)8Brd^Trp53-Wnt3, Trp53-Wnt3 inversion
• Gene: In(11Trp53;11Wnt3)8Brd Location: unknown Genetic Position: Chr11, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:56548
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2
• Project Collection: Mutagenesis for Dev. Defects

Mutation description

• Allele Type: Targeted
• Mutation: Inversion
• In(11Trp53;11Wnt3)8Brd involves 1200 genes/genome features (n-TQttg2, 4930406D14Rik, Gm11612 ...) View all
• Mutation details: This 24-cM inversion on Chr 16 was generated by Cre-recombinase mediated recombination between oppositely-oriented loxP sites in Wnt3^tm2Brd and Trp53^tm2Brd. (J:56548)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any In(11Trp53;11Wnt3)8Brd Mutation: 4 strains or lines available

References

• Original: J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
• All: 5 reference(s)