Cd4ts1^BALB/c
QTL Variant Detail

Summary

• QTL variant: Cd4ts1^BALB/c
• Name: CD4 T cell subset 1; BALB/c
• MGI ID: MGI:2673472
• QTL: Cd4ts1 Location: Chr3:56704102-56704231 bp Genetic Position: Chr3, cM position of peak correlated region/allele: 27.32 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: BALB/c

Variant description

• Allele Type: QTL
• Mutation: Undefined
• Mutation details: This allele confers increased proportion of CD4 T cells in 8 month old vigin mice compared to C57BL/6. (J:83220)

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:83220

Interval mapping was performed on a (BALB/c x C57BL/6)F1 x (C3H x DBA/2)F1 cross to identify QTLs affecting the level of T cell subsets in virgin and mated animals at 8 and 18 months of age. A QTL associated with CD4 T cell subset levels, Cd4ts1, mapped to 29.5 cM (D3Mit25) on mouse Chromosome 3 with statistical significance of P<0.05. Cd4ts1 is associated with CD4 T cell levels in 8 month old virgin mice.

References

• Original: J:83220 Jackson AU, et al., Genetic polymorphisms in mouse genes regulating age-sensitive and age-stable T cell subsets. Genes Immun. 2003 Jan;4(1):30-9
• All: 1 reference(s)