Atp6v1b1^tm1Choo
Targeted Allele Detail

Summary

• Symbol: Atp6v1b1^tm1Choo
• Name: ATPase, H+ transporting, lysosomal V1 subunit B1; targeted mutation 1, Daniel Choo
• MGI ID: MGI:2673510
• Synonyms: Atp6b1^-, Atp6v1b1-, Atp6v1b1^tm1Rpl
• Gene: Atp6v1b1 Location: Chr6:83719999-83735837 bp, + strand Genetic Position: Chr6, 35.94 cM
• Alliance: Atp6v1b1^tm1Choo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:84744
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 7 through 11 were replaced with a neomycin selection cassette. (J:84744, J:101414)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atp6v1b1 Mutation: 32 strains or lines available

References

• Original: J:84744 Dou H, et al., Mice lacking the B1 subunit of H+ -ATPase have normal hearing. Hear Res. 2003 Jun;180(1-2):76-84
• All: 17 reference(s)