Kcnk5^{Gt(pGT1.8TM)1Gray}
Gene trapped Allele Detail

Summary

• Symbol: Kcnk5^{Gt(pGT1.8TM)1Gray}
• Name: potassium channel, subfamily K, member 5; gene trap 1, Andrew T Gray
• MGI ID: MGI:2673542
• Synonyms: KCNK5^-, task2-
• Gene: Kcnk5 Location: Chr14:20190125-20231850 bp, - strand Genetic Position: Chr14, 11.43 cM, cytoband A3
• Alliance: Kcnk5^{Gt(pGT1.8TM)1Gray} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:85252
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The pGT1.8TM gene trap vector containing splice acceptor sequence upstream of a lacZ reporter construct integrated into an intron of the endogenous locus. Mutant transcript was identified by RT-PCR analysis. (J:85252)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcnk5 Mutation: 62 strains or lines available

References

• Original: J:85252 Gerstin KM, et al., Mutation of KCNK5 or Kir3.2 potassium channels in mice does not change minimum alveolar anesthetic concentration. Anesth Analg. 2003 May;96(5):1345-9, table of contents
• All: 7 reference(s)