Serpinb6a^tm1.1Pib
Targeted Allele Detail

Summary

• Symbol: Serpinb6a^tm1.1Pib
• Name: serine (or cysteine) peptidase inhibitor, clade B, member 6a; targeted mutation 1.1, Phillip I Bird
• MGI ID: MGI:2673997
• Gene: Serpinb6a Location: Chr13:34101901-34186777 bp, - strand Genetic Position: Chr13, 14.0 cM
• Alliance: Serpinb6a^tm1.1Pib page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:85039
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The floxed neo cassette immediately downstrean of EGFP was excised from Serpinb6a^tm1Pib via cre mediated recombination in vitro. Expression of GFP recapitulated endogenous expression. Western blot analysis indicated an absence of normal protein in homozygous mutant spleen and thymus tissue. (J:85039)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Serpinb6a Mutation: 26 strains or lines available

References

• Original: J:85039 Scarff KL, et al., A retained selection cassette increases reporter gene expression without affecting tissue distribution in SPI3 knockout/GFP knock-in mice. Genesis. 2003 Jul;36(3):149-57
• All: 3 reference(s)