Racgap1^{Gt(pSABetageo)11Huy}
Gene trapped Allele Detail

Summary

• Symbol: Racgap1^{Gt(pSABetageo)11Huy}
• Name: Rac GTPase-activating protein 1; gene trap 11, Danny Huylebroeck
• MGI ID: MGI:2674133
• Synonyms: gtl11
• Gene: Racgap1 Location: Chr15:99518377-99549504 bp, - strand Genetic Position: Chr15, 56.13 cM
• Alliance: Racgap1^{Gt(pSABetageo)11Huy} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:69359
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap vector inserted into the second coding exon of the gene such that splicing occurred between an exon from the gene to a splice acceptor site in the inserted vector. A fusion protein of the endogenous gene to the beta-galactosidase of the inserted vector sequences is expressed from this allele. (J:69359)

Expression

In Mice Carrying this Mutation:	23 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Racgap1 Mutation: 38 strains or lines available

References

• Original: J:69359 Van de Putte T, et al., Mice with a homozygous gene trap vector insertion in mgcRacGAP die during pre-implantation development. Mech Dev. 2001 Apr;102(1-2):33-44
• All: 1 reference(s)