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Brd4Gt(pGT1.8TM)ST132Nimr
Gene trapped Allele Detail
Summary
Symbol: Brd4Gt(pGT1.8TM)ST132Nimr
Name: bromodomain containing 4; gene trap ST132, National Institute for Medical Research
MGI ID: MGI:2674141
Synonyms: Brd4gt
Gene: Brd4  Location: Chr17:32415248-32503696 bp, - strand  Genetic Position: Chr17, 17.39 cM, cytoband B2
Alliance: Brd4Gt(pGT1.8TM)ST132Nimr page
Mutation
origin
Mutant Cell Line:  ST132
Germline Transmission:  Earliest citation of germline transmission: J:76662
Parent Cell Line:  CGR8 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT1.8TM
 
Mutation detailsA gene trap vector inserted into the second intron of the gene. An RNA consisting of sequences from exons 1 and 2 fused to the vector sequences is predicted to be expressed from this allele. beta-galactosidase is expressed from this allele under the control of the endogenous gene promoter. (J:76662)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 12 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Brd4 Mutation:  106 strains or lines available
References
Original:  J:76662 Houzelstein D, et al., Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4. Mol Cell Biol. 2002 Jun;22(11):3794-802
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory