Meox2^tm1Vpa
Targeted Allele Detail

Summary

• Symbol: Meox2^tm1Vpa
• Name: mesenchyme homeobox 2; targeted mutation 1, Vassilis Pachnis
• MGI ID: MGI:2674242
• Synonyms: Meox2^tm1Pach, Mox2^-
• Gene: Meox2 Location: Chr12:37158539-37229533 bp, + strand Genetic Position: Chr12, 16.84 cM
• Alliance: Meox2^tm1Vpa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:56172
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette inserted by homologous recombination replaced exon 1. Transcript was undetected by Northern blot analysis of RNA obtained from homozygous mutant heart, kidney, lung, and liver tissue. (J:56172)

Expression

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Meox2 Mutation: 18 strains or lines available

References

• Original: J:56172 Mankoo BS, et al., Mox2 is a component of the genetic hierarchy controlling limb muscle development. Nature. 1999 Jul 1;400(6739):69-73
• All: 10 reference(s)