Meox1^tm1Bmk
Targeted Allele Detail

Summary

• Symbol: Meox1^tm1Bmk
• Name: mesenchyme homeobox 1; targeted mutation 1, Baljinder S Mankoo
• MGI ID: MGI:2674273
• Synonyms: Meox1^-, Meox1^tm1BSM
• Gene: Meox1 Location: Chr11:101768336-101785200 bp, - strand Genetic Position: Chr11, Syntenic
• Alliance: Meox1^tm1Bmk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:84754
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 1, which includes the start codon, and 2.3 kb of upstream intronic sequence was deleted by homologous recombination of a targeting vector. Transcript was reported to be undetected in homozygous mutant mice. (J:84754)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Meox1 Mutation: 17 strains or lines available

References

• Original: J:84754 Mankoo BS, et al., The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somites. Development. 2003 Oct;130(19):4655-64
• All: 4 reference(s)