Tg(Hoxb7-cre)13Amc
Transgene Detail

Summary

• Symbol: Tg(Hoxb7-cre)13Amc
• Name: transgene insertion 13, Andrew P McMahon
• MGI ID: MGI:2675121
• Synonyms: Hoxb7-Cre, HoxB7/Cre, HoxB7Cre
• Transgene: Tg(Hoxb7-cre)13Amc Location: unknown
• Alliance: Tg(Hoxb7-cre)13Amc page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Hoxb7-cre)13Amc expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Hoxb7 (MGI:96188)

• Mutation details: A transgenic construct containing the 1.3Kb enhancer and promoter sequence upstream of the of mouse homeo box B7 gene, a human growth factor mini gene and the Cre coding sequence was injected into fertilized C57BL/6 mouse eggs. Cre recombinase expression is detected in the mesonephric duct as early as embryonic day 9.5, in the ureteric bud by embryonic day 10.25 and in all ureteric bud epithelial cells by embryonic day 12.5. Low levels of expression are detected in the dorsal root ganglia and the spinal cord. (J:79481, J:100575)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Hoxb7 (mouse) Summary of all recombinase alleles driven by Hoxb7. Comparative matrix view of recombinase activities Alliance mouse Hoxb7 gene page

Disease models

Expression

In Mice Carrying this Mutation:

107 assay results 6 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:79481 Yu J, et al., Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney. Development. 2002 Nov;129(22):5301-12
• All: 115 reference(s)