Ccne2^tm1Pisc
Targeted Allele Detail

Summary

• Symbol: Ccne2^tm1Pisc
• Name: cyclin E2; targeted mutation 1, Piotr Sicinski
• MGI ID: MGI:2675474
• Synonyms: Cyclin E2^-
• Gene: Ccne2 Location: Chr4:11191351-11204779 bp, + strand Genetic Position: Chr4, 5.07 cM, cytoband A2
• Alliance: Ccne2^tm1Pisc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:85224
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Coding exons 1-8 were replaced with a puromycin resistance gene. (J:85224)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccne2 Mutation: 32 strains or lines available

References

• Original: J:85224 Geng Y, et al., Cyclin E ablation in the mouse. Cell. 2003 Aug 22;114(4):431-43
• All: 14 reference(s)