Vac14^ingls
Spontaneous Allele Detail

Summary

• Symbol: Vac14^ingls
• Name: Vac14 homolog (S. cerevisiae); infantile gliosis
• MGI ID: MGI:2675671
• Synonyms: ingls, Vac14^L156R
• Gene: Vac14 Location: Chr8:111345217-111447030 bp, + strand Genetic Position: Chr8, 57.59 cM
• Alliance: Vac14^ingls page

Mutation origin

• Strain of Origin: DBA/2J

Mutation description

• Allele Type: Spontaneous (Hypomorph)
• Mutation: Single point mutation
• Mutation details: Exon 4 contains a T-to-C transition at position 467 (c.467T>G) that results in an amino acid substitution of leucine with arginine at position 156 (p.L156R). This allele is hypomorphic. (J:142703)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Vac14 Mutation: 43 strains or lines available

Notes

This spontaneous mutation arose in 1991 at The Jackson Laboratory.

References

• Original: J:81516 Bronson R, et al., Infantile gliosis (ingls) a new spontaneous mutation in the mouse. Mouse Mutant Resources Web Site, The Jackson Laboratory, Bar Harbor, Maine. MGI Direct Data Submission. 2003
• All: 5 reference(s)