Ablim1tm1Tili
Targeted Allele Detail
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Symbol: |
Ablim1tm1Tili |
Name: |
actin-binding LIM protein 1; targeted mutation 1, Tiansen Li |
MGI ID: |
MGI:2676007 |
Synonyms: |
abLIM-L - |
Gene: |
Ablim1 Location: Chr19:57021165-57303351 bp, - strand Genetic Position: Chr19, 52.09 cM
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Alliance: |
Ablim1tm1Tili page
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Germline Transmission: |
Earliest citation of germline transmission:
J:84905
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129/Sv
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Allele Type: |
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Targeted (Modified isoform(s), Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Elimination of the retina-specific L isoform was accomplished by replacing all of exon 1 and 18 bp of intron 1 with a cassette containing IRES-lacZ and MC1-neo. RT-PCR analysis of homozygous mutant mice showed that while transcripts encoding the M and S isoforms were present, transcript encoding the L isoform was absent. Reporter expression was observed but sporadic.
(J:84905)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ablim1 Mutation: |
56 strains or lines available
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Original: |
J:84905 Lu C, et al., Normal retinal development and retinofugal projections in mice lacking the retina-specific variant of actin-binding LIM domain protein. Neuroscience. 2003;120(1):121-31 |
All: |
1 reference(s) |
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