Gata1^tm1Phi
Targeted Allele Detail

Summary

• Symbol: Gata1^tm1Phi
• Name: GATA binding protein 1; targeted mutation 1, Sjaak Philipsen
• MGI ID: MGI:2677342
• Gene: Gata1 Location: ChrX:7825504-7842844 bp, - strand Genetic Position: ChrX, 3.59 cM, cytoband A2
• Alliance: Gata1^tm1Phi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:85598
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Single loxP sites were inserted into intron 1 and downstream of exon 6 in the 3' flanking region of the gene. A cassette containing a splice acceptor, cDNA encoding GFP, and a neomycin resistance gene were inserted downstream of the 3' loxP site. (J:85598)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gata1 Mutation: 45 strains or lines available

References

• Original: J:85598 Lindeboom F, et al., A tissue-specific knockout reveals that Gata1 is not essential for Sertoli cell function in the mouse. Nucleic Acids Res. 2003 Sep 15;31(18):5405-12
• All: 12 reference(s)