Ovgp1^tm1Yar
Targeted Allele Detail

Summary

• Symbol: Ovgp1^tm1Yar
• Name: oviductal glycoprotein 1; targeted mutation 1, Yoshihiko Araki
• MGI ID: MGI:2677401
• Synonyms: ogp^-
• Gene: Ovgp1 Location: Chr3:105881118-105894739 bp, + strand Genetic Position: Chr3, 46.46 cM, cytoband F3
• Alliance: Ovgp1^tm1Yar page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:85457
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1-6 were replaced with a neomycin resistance gene. Northern blot analysis then demonstrated the absence of mRNA transcripts in total RNA prepared from oviducts of homozygous animals. (J:85457)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ovgp1 Mutation: 55 strains or lines available

References

• Original: J:85457 Araki Y, et al., Effect of a null mutation of the oviduct-specific glycoprotein gene on mouse fertilization. Biochem J. 2003 Sep 1;374(Pt 2):551-7
• All: 2 reference(s)