Bc1^tm1Jbro
Targeted Allele Detail

Summary

• Symbol: Bc1^tm1Jbro
• Name: brain cytoplasmic RNA 1; targeted mutation 1, Jurgen Brosius
• MGI ID: MGI:2677614
• Gene: Bc1 Location: Chr7:144468207-144468360 bp, + strand Genetic Position: Chr7, Syntenic
• Alliance: Bc1^tm1Jbro page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:85467
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The endogenous gene was replaced with a neomycin selection cassette inserted by homologous recombination. Northern blot analysis confirmed the absence of transcript in homozygous mutant mice. (J:85467)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bc1 Mutation: 1 strain or line available

References

• Original: J:85467 Skryabin BV, et al., Neuronal untranslated BC1 RNA: targeted gene elimination in mice. Mol Cell Biol. 2003 Sep;23(18):6435-41
• All: 9 reference(s)