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Bag4tm1Kpf
Targeted Allele Detail
Summary
Symbol: Bag4tm1Kpf
Name: BCL2-associated athanogene 4; targeted mutation 1, Klaus Pfeffer
MGI ID: MGI:2677764
Synonyms: Sodd-
Gene: Bag4  Location: Chr8:26254566-26275237 bp, - strand  Genetic Position: Chr8, 14.17 cM, cytoband A3
Alliance: Bag4tm1Kpf page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:85442
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsStarting shortly after the start codon, exon 1 was replaced by a neomycin resistance cassette in opposite orientation. Western blot analysis of liver protein extracts confirmed the absence of translation product. (J:85442)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bag4 Mutation:  33 strains or lines available
References
Original:  J:85442 Endres R, et al., Apparently normal tumor necrosis factor receptor 1 signaling in the absence of the silencer of death domains. Mol Cell Biol. 2003 Sep;23(18):6609-17
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory